Abstract:Abstract: Chronic kidney disease (CKD) is a global health burden with high economic costs. Cardiovascular disease (CVD) is the most common cause of death in CKD patients, and vascular calcification plays an extremely important role in CKD patients with CVD. When the imbalance between factors that promote calcification and restrain calcification occurs in the body, a series of vascular endothelial cell reactions will be activated to promote vascular calcification. Recently, it has been found that adipokines play important roles in the occurrence and development of vascular calcification in CKD patients. Herein, the effects of various adipokines on vascular calcification in CKD are described, with the hope of providing new ideas for prevention and treatment of vascular calcification in CKD.
引用本文:
刘世贞, 刘璠娜. 脂肪因子在慢性肾脏病血管钙化中的作用[J]. 生命科学研究, 2020, 24(1): 68-74.
LIU Shi-zhen, LIU Fan-na. The Role of Adipokines in Vascular Calcification of Chronic Kidney Disease . Life Science Research, 2020, 24(1): 68-74.