Abstract：Spinal cord injury (SCI) can cause neurological dysfunction below the injury level, which seriously affects the patient’s quality of life. Heat shock proteins (HSPs) are one kind of the important molecules that protect cells or tissues from further injury after stress in the body. The expression of HSPs is increased after spinal cord injury, and the proteins can slow down further aggravation of spinal cord injury by promoting angiogenesis and inhibiting inflammatory response, neuron apoptosis and oxidative stress. Herein, the production and function mechanisms of HSPs after spinal cord injury are reviewed to provide reference for the related research in the future.
引用本文:
贺学岗, 张广智, 马占军, 高一诚, 郭旭东, 康学文. 热休克蛋白在脊髓损伤中的研究进展[J]. 生命科学研究, 2020, 24(4): 339-344.
HE Xue-gang, ZHANG Guang-zhi, MA Zhan-jun, GAO Yi-cheng, GUO Xu-dong, KANG Xue-wen. Research Progresses of Heat Shock Proteins in Spinal Cord Injury. Life Science Research, 2020, 24(4): 339-344.
