Abstract:Biomineralization is an important and special physiological process in life system. There are a variety of biological mineralization products in living organisms, from the well-known bones and teeth to metal oxides at the nanoscale. The major difference between biomineralization and normal mineralization is the involvement of biomolecules, metabolic products, various cells and biomatrix in the mineral formation process. A variety of biological factors participate in biomineralization. These factors not only make the reaction conditions mild, but also give the reaction products better material properties and biocompatibility. The most typical example is that magnetotactic bacteria can form magnetosomes, i.e, membrane-coated magnetic nanocrystals with uniform size and a single magnetic domain through the biomineralization process. Herein, the role and function of the important magnetosome membrane proteins of magnetotatic bacteria and the iron carrier protein (ferritin) in the process of magnetite biomineralization are summarized. The in-depth studying of the biomineralizaed process of magnetotatic bacteria would reveal the molecular mechanism of biological macromolecules in regulating the growth of inorganic minerals, and provide an important theoretical basis for the biomimetic synthesis of new biomaterials.
引用本文:
崔琪琪, 陶童祥, 马 坤. 趋磁细菌蛋白参与磁铁矿生物矿化机制的研究进展[J]. 生命科学研究, 2020, 24(4): 327-333.
CUI Qi-qi, TAO Tong-xiang, MA Kun. Research Progress in Protein Mediated Biomineralization of Magnetotactic Bacteria. Life Science Research, 2020, 24(4): 327-333.