Abstract:Whether the new coronavirus (SARS-CoV-2) vaccine will be successfully developed has attracted attention of the whole world. In general, most infected patients can clear the virus from their bodies and finally recover, and the convalescent plasma collected from recovered people has a therapeutic effect on severe cases of COVID-19. These facts indicate that the viral infection can induce protective immunity in humans, and that vaccines would be successfully developed. However, there is a major concern that vaccination to the virus may cause antibody-dependent enhancement (ADE), which would result in failure of the vaccine development. And immune-mediated lung injury may be another concern about the virus vaccines. Nowadays, there are many types of vaccines, including traditional vaccines and novel ones. In theory, all types of vaccines and various methods can be tried in the research and development of SARS-CoV-2 vaccines.
引用本文:
陈 则. 关于新冠病毒疫苗研发的思考[J]. 生命科学研究, 2020, 24(4): 259-262.
CHEN Ze. Thoughts on COVID-19 Related Vaccine Research. Life Science Research, 2020, 24(4): 259-262.