Abstract:Abstract: Bone marrow mesenchymal stem cells (BMSCs) are mainly found in the bone marrow and have multi-differentiation and proliferation potential. They closely correlate with tumors. In addition to their tumor tropism, they can also affect tumor cell growth and proliferation, migration and metastasis, and angiogenesis. They play an important role in the regulation and development of tumors. At the same time, more and more attention has been paid to the application of BMSCs in tumor gene therapy and immunotherapy, providing novel ideas for cancer therapy. Herein, effects of BMSCs on tumorigenesis and development, as well as their applications in tumor therapy, are reviewed.
引用本文:
胡星遥, 孙慧娟, 朱 静, 张 洁, 尚广彬. 骨髓间充质干细胞在肿瘤发生及治疗作用中的研究进展[J]. 生命科学研究, 2020, 24(2): 147-152.
HU Xing-yao, SUN Hui-juan, ZHU Jing, ZHANG Jie, SHANG Guang-bin. Research Progress of Bone Marrow Mesenchymal Stem Cells in Tumorigenesis and Therapeutic Effects. Life Science Research, 2020, 24(2): 147-152.