Abstract：Abstract: Exosomes are extracellular vesicles (EVs) in the central nervous system (CNS) and are involved in regulation of cell information under physiological and pathological conditions. A number of studies have shown that exosomes secreted by neural stem cells (NSCs) can be used as biomarkers for the diagnosis of neu-rological diseases and carriers for therapeutic drug delivery, and may play a vital role in the prevention and treatment of neurological diseases. Herein, the synthesis, basic characteristics, isolation and purification of exosomes are described, among which the characteristics of exosomes secreted by NSCs and their roles in the diagnosis and treatment of neurological diseases are highlighted. The challenges in using exosomes as a new tool in neurological diseases are summarized.
引用本文:
江张胜, 赵晨玲, 董 婷. 神经干细胞来源的外泌体在神经疾病诊治中的应用[J]. 生命科学研究, 2022, 26(3): 271-275.
JIANG Zhang-sheng, ZHAO Chen-ling, DONG Ting. Application of Neural Stem Cell-derived Exosomes in Diagnosis and Treatment of Neurological Diseases . Life Science Research, 2022, 26(3): 271-275.
