Abstract:Abstract: Erythrocytes undergo programmed cell death, similar to apoptosis, known as eryptosis. Eryptosis results from a wide variety of contributors and is characterized by phosphatidylserine (PS) exposure, cell shrinkage, and the presence of membrane blebbing. Erythrocytes with PS exposure are bound to and engulfed by macrophages in a PS-dependent manner. The liver as the primary organ supports rapid erythrocyte removal. Research on molecular mechanisms dictating eryptosis would help reveal the physiological and pathological significance of eryptosis in liver.
引用本文:
徐 薇, 彭 芳, 李 宁. 红细胞衰亡及其在肝脏中的识别与清除机制[J]. 生命科学研究, 2019, 23(2): 135-139.
XU Wei, PENG Fang, LI Ning. The Recognition and Removal Mechanism of Eryptosis in Liver. Life Science Research, 2019, 23(2): 135-139.