Abstract:Exosome, a kind of 40~100 nm particle enclosed by a phospholipid bilayer, is released by various types of cells. Exosome is composed of liposomes, proteins, DNA, miRNA and so on. A number of studies have revealed that exosomes are involved in many important physiological and pathological processes especially in the metastasis of tumors by carrying biomolecules. Exosomes play an important role in the metastasis of tumors via initiating the metastasis of tumors, promoting tumor angiogenesis, participating in the regulation of tumor premetastatic microenvironment and the immune regulation of tumor microenvironment.
引用本文:
宋丽杰, 王 丽, 王 捷. 外泌体在肿瘤侵袭转移中作用的研究进展[J]. 生命科学研究, 2018, 22(4): 326-331.
SONG Li-jie, WANG Li, WANG Jie. Progress of Exosomes in Tumor Metastases. Life Science Research, 2018, 22(4): 326-331.