Abstract:Abstract: MicroRNAs (miRNAs) are a group of small RNAs with a length of 18~25 nucleotides that are widely present in eukaryotes and are produced by transcription of DNA. They are endogenous non-coding small RNAs and play an important role in some important life activities. For example, when the expression of miRNAs is downregulated, the body will be more susceptible to cancer and other diseases. This phenomenon enables us to make early diagnosis of disease through quantitative detection of miRNAs. Herein, the research progress of miRNA detection techniques based on the principles of hybridization, amplification and sequencing was described.
引用本文:
蓝 琳, 喻 芬, 黄明敏, 孟祥贤. miRNA定量检测方法的研究进展[J]. 生命科学研究, 2018, 22(6): 491-495.
LAN Lin, YU Fen, HUANG Ming-min, MENG Xiang-xian. Research Progresses of miRNA Quantitative Detection Methods. Life Science Research, 2018, 22(6): 491-495.