Abstract:Abstract: Pseudomonas aeruginosa is a major opportunistic pathogen that can cause acute or chronic infection in clinic. The type Ⅵ secretion system (T6SS) is an important secretion system that secretes a variety of virulence proteins into environment or eukaryotic cells and promotes the formation of envelope in P. aeruginosa. T6SS plays an important role in the pathogenicity and drug resistance of P. aeruginosa. It can transport not only toxic proteins but also metal ions, thereby relieving the bacterial environmental pressure and survival competition. Herein, the structure, regulation and Fe ion transport mechanism of T6SS in P. aeruginosa are discussed.
引用本文:
王瑞营, 张 娟, 王 碧, 侯亚文, 吴斌艳, 扈会整. 铜绿假单胞菌中Ⅵ型分泌系统及其参与铁离子转运机制的研究进展[J]. 生命科学研究, 2020, 24(5): 404-409.
WANG Rui-ying, ZHANG Juan, WANG Bi, HOU Ya-wen, WU Bin-yan, HU Hui-zheng. Research Progress in the Type Ⅵ Secretion System of Pseudomonas aeruginosa and Mechanism of Its Participation in Transport of Iron Ions . Life Science Research, 2020, 24(5): 404-409.