Abstract:Abstract: Septic encephalopathy is brain dysfunction mediated by the septic inflammatory response. It appears in patients with multiple organ dysfunction syndrome (MODS). Septic encephalopathy is associated with many kinds of inflammatory cytokines and chemicals. These inflammatory molecules induce systemic inflammatory response, trigger blood-brain barrier disruption and affect the brain function, leading to neurological symptoms such as aberrant synaptic transmission and plasticity. Herein, the imbalance of neurotransmitter, impairment of synaptic transmission, effect of nervous regulation and application of quantum dots in septic encephalopathy are summarized, aiming at facilitating its future research.
引用本文:
金 晔, 赵博伦, 韩晓菲, 刘庆平, 王 欢. 脓毒性脑病的神经化学机制研究进展[J]. 生命科学研究, 2019, 23(3): 219-225.
JIN Ye, ZHAO Bo-lun, HAN Xiao-fei, LIU Qing-ping, WANG Huan. The Progress of Neurochemical Mechanisms in Septic Encephalopathy. Life Science Research, 2019, 23(3): 219-225.