Abstract:Abstract: Domestic and international epidemiological researches have shown that the incidence rates of both type 2 diabetes mellitus and colorectal cancer are increasing gradually, and there may exist a correlation between these two diseases. To clarify this, the studies concerning the relationship between diabetes and colorectal cancer were summarized here, including their common risk factors, such as gender differences, unhealthy lifestyle, the family history of diseases, insulin treatment, etc., and the related molecular mechanisms such as insulin-like growth factor, hyperinsulinemia, chronic inflammation and oxidative stress, long non-coding RNA and autophagy.
引用本文:
赵 明, 习 阳, 步世忠. 2型糖尿病与结直肠癌相关性的研究进展[J]. 生命科学研究, 2016, 20(4): 365-370.
ZHAO Ming, XI Yang, BU Shi-Zhong. Research on the Correlation Between Type 2 Diabetes Mellitus and Colorectal Cancer. Life Science Research, 2016, 20(4): 365-370.