Abstract:Abstract: The assisted reproductive technology (ART) brings hope to patients with infertility. However, it also brings offspring sex ratio imbalance. Relative risk factors affecting sex ratio of live births still need to be studied. The clinical data of 3 462 cycles gaining 4 635 babies, collected from Jan. 2013 to Dec. 2014 in the Third Affiliated Hospital of Guangzhou Medical University, were analyzed. There was no significant difference in offspring sex ratio between IVF and ICSI groups (P=0.07). Further analysis showed that PESA/TESA-ICSI was significantly correlated with a decreased percentage of male babies (P=0.036). Meanwhile, a higher male birth rate following blastocyst transfer was found, compared with that of cleavage-stage embryo transfer (P=0.005). Moreover, the stratified chi-square test analyses confirmed that the stage of transferred embryo was really one of the factors influencing sex ratio at birth after eliminating the disturbance of insemination (P=0.021). But none of the above factors could be an independent predictor with the multivariate analysis. Collectively, the blastocyst transfer preferred a male baby, while PESA/TESA-ICSI correlated to a decreased proportion of male babies.
引用本文:
李 磊, 姚亚超, 刘寒艳, 黄玉玲. ART中影响新生儿性别比的相关因素分析[J]. 生命科学研究, 2017, 21(3): 228-232.
LI Lei, YAO Ya-Chao, LIU Han-Yan, HUANG Yu-Ling. Factors Affecting Offspring Sex Ratio in ART. Life Science Research, 2017, 21(3): 228-232.