Abstract:Abstract: To explore the bioinformatic characteristics, pathogenicity and drug resistance of Salmonella in fresh chicken, a Salmonella strain FC10727 was isolated from a fresh chicken purchased from an agricultural market in Changsha City. Illumina HiSeq 4000 and PacBio were used for whole genome sequencing and bioinformatics analysis of FC10727. Its genome was found to have 4 638 420 base pairs, with 54.15% GC content, and was predicted to encode 4 016 genes. There were 944 corresponding genes found in the eggNOG library, which can be divided into 20 categories based on their functions. In the KEGG library, there were 2 981 related genes participating in a total of 24 types of metabolic pathways. In the GO library, a total of 2 901 related genes were obtained, which can be divided into 42 categories. In the CAZy library, there were 96 related genes which can be divided into 5 categories. The strain has 14 drug resistance genes, with multiple drug resistance mechanisms such as β-lactam drug resistance. And it also has 27 pathogenic genes, including systemic lupus erythematosus pathogenic genes and multiple pathogenic factors.
引用本文:
宋 晟, 张海韵, 郭焜鹏, 王芳斌. 一株鸡源性沙门氏菌的基因组分析[J]. 生命科学研究, 2021, 25(3): 268-275.
SONG Sheng, ZHANG Hai-yun, GUO Kun-peng, WANG Fang-bin. Genome Analysis of a Chicken-derived Salmonella. Life Science Research, 2021, 25(3): 268-275.