Research Advances in Cryopreservation of Non-human Primate Sperm
1. Medical Research Center, Fujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center), Fuzhou 350011, Fujian, China; 2. Medical Research Center, Fujian Maternity and Child Health Hospital, Fuzhou 350001, Fujian, China; 3. NHC Key Laboratory of Technical Evaluation of Fertility Regulation for Non-human Primate (Fujian Maternity and Child Health Hospital), Fuzhou 350013, Fujian, China
Abstract：With the development of biomedical technology, non-human primate (NHP) models become increa-singly widely used in basic scientific research. Meanwhile, many NHP species are on the verge of extinction due to habitat destruction, hunting and genetic isolation. Thus, it is important to improve the sperm cryop-reservation technology to conserve the genetic resources. This review mainly described the characteristics of NHP semen, introduced the methods of semen liquefaction and quality evaluation, and analyzed the effects of cryoprotectants, extenders and freezing methods on sperm cryopreservation. It also compared the relevant sperm parameters, discussed the puzzles and difficulties in sperm cryopreservation research, and proposed some feasible solutions. In conclusion, this paper reviewed the important research results of NHP sperm cryop-reservation in recent years, which may have certain reference value for development of NHP sperm cryopro-tectants and cryopreservation technology.
范晓静, 魏雅岚, 王心睿. 非人灵长类动物精子冻存技术的研究进展[J]. 生命科学研究, 2023, 27(4): 330-337.
FAN Xiaojing, WEI Yalan, WANG Xinrui. Research Advances in Cryopreservation of Non-human Primate Sperm. Life Science Research, 2023, 27(4): 330-337.
