Abstract:Abstract: The activated inflammatory neutrophils will actively release a kind of beads like fibrous network materials during the period of infection by bacteria, fungi or parasites or during inflammatory response. This phenomenon is called neutrophil extracellular traps (NETs) and the process of its formation is called NETosis. NETs can kill pathogens or prevent their local spread in host tissues, but a large number of NETs may also cause local or systemic damage. Recent studies have shown that viruses can also induce NETosis, and the resulting NETs also have some antiviral effects, but the role of NETs in controlling virus infection is not clear. Herein, the mechanism of virus-induced NET formation and the antiviral effects of NETs were reviewed.
引用本文:
李汶霖, 李淑凝, 王 洋, 沈海娥, 李志敏. 中性粒细胞胞外诱捕网(NETs)在抗病毒免疫作用中的研究进展与展望[J]. 生命科学研究, 2020, 24(6): 511-516.
LI Wen-lin, LI Shu-ning, WANG Yang, SHEN Hai-e, LI Zhi-min. Research Progress and Prospect of the Role of Neutrophil Extracellular Traps (NETs) in Antiviral Immunity. Life Science Research, 2020, 24(6): 511-516.